Product Information
    
 
    

    

        

            

                

                
Product Name
                
                

                
Cat#
                
                

                
Size
                
                

                
Price（¥）
                
            
            

                

                
Recombinant Human Interleukin-10 (Human IL-10)
                
                

                
90109ES10
                
                

                
10 μg
                
                

                
1855.00
                
            
            

                

                
90109ES60
                
                

                
100 μg
                
                

                
13615.00
                
            
            

                

                
90109ES76
                
                

                
500 μg
                
                

                
35395.00
                
            
        
    
    
    
 
    
Product Description
    
 
    
Interleukin-10 (IL-10), also known as cytokine synthesis inhibitory factor (CSIF), is the charter member of the IL-10 family of α-helical cytokines that also includes IL-19, IL-20, IL-22, IL-24, and IL-26/AK155. IL-10 is a 178 amino acid molecule that contains two intrachain disulfide bridges and is expressed as a 36 kDa noncovalently associated homodimer. Mature human IL10 shares 72%86% amino acid sequence identity with bovine, canine, equine, feline, mouse, ovine, porcine, and rat IL10. IL-10, a cytokine produced by CD4+ T lymphocytes belonging to the Th-2 subset, has previously been shown to inhibit the synthesis of IFN-gamma by both T cells and NK cells.The anti-inflammatory actions of IL-10 may be therapeutically useful either directly or through modulation of HO-1 activity.
    
 
    
Product Properties
    
 
    

    

        

            

                

                
Synonyms
                
                

                
Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, IL10A, TGIF, CSIF,
                
            
            

                

                
Accession
                
                

                
P22301
                
            
            

                

                
GeneID
                
                

                
3586
                
            
            

                

                
Source
                
                

                
E.coli-derived human IL-10 protein, Ser19-Asn178.
                
            
            

                

                
Molecular Weight
                
                

                
Approximately 18.6 kDa.
                
            
            

                

                
AA Sequence
                
                

                
SPGQGTQSEN SCTHFPGNLP NMLRDLRDAF SRVKTFFQMK DQLDNLLLKE SLLEDFKGYL GCQALSEMIQ FYLEEVMPQA ENQDPDIKAH VNSLGENLKT LRLRLRRCHR FLPCENKSKA VEQVKNAFNK LQEKGIYKAM SEFDIFINYI EAYMTMKIRN
                
            
            

                

                
Tag
                
                

                
None
                
            
            

                

                
Physical Appearance
                
                

                
Sterile Filtered White lyophilized (freeze-dried) powder.
                
            
            

                

                
Purity
                
                

                
> 95% by SDS-PAGE and HPLC analyses.
                
            
            

                

                
Biological Activity
                
                
TUNEology 波长可调检测卡盒-->