Recombinant Human NT-4 Protein-细胞/细菌培养-试剂-生物在线
翌圣生物科技(上海)股份有限公司
Recombinant Human NT-4 Protein

Recombinant Human NT-4 Protein

商家询价

产品名称: Recombinant Human NT-4 Protein

英文名称: Recombinant Human NT-4 Protein

产品编号: 92114ES05

产品价格: 535.00

产品产地: Yeasen

品牌商标: Yeasen

更新时间: 2024-12-10T11:18:52

使用范围: null

规格 价格
2μg 535.0
10 μg 1655.0
50μg 4135.0
100 μg 6205.0
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Product Information

Product Name

Cat#

Size

Recombinant Human NT-4 Protein

92114ES05

2 μg

92114ES10

10 μg

92114ES50

50 μg

92114ES60

100 μg

 

Product Description

Neurotrophin-4 (NT-4), is a member of the NGF family of neuronal and epithelial growth factors. Neurotrophins have six conserved cysteine residues that are involved in the formation of three disulfide bonds.Mature human NT-4 shares 91% and 95% aa sequence identity with mouse and rat NT-4/5, respectively. The mature protein is secreted as a homodimer and can also form heterodimers with BDNF or NT-3. NT-4 binds and induces receptor dimerization and activation of TrkB. NT-4 promotes the development and survival of selected peripheral and CNS neurons.

 

Product Properties

Synonyms

Neurotrophin-5, NT-5Neurotrophin-4 ;GLC10

Accession

P34130

GeneID

4909

Source

E.coli-derived Human NT-4, G81-A210, with an N-terminal Met.

Molecular Weight

Approximately 28.1 kDa.

AA Sequence

MGVSETAPAS RRGELAVCDA VSGWVTDRRT AVDLRGREVE VLGEVPAAGG SPLRQYFFET RCKADNAEEG GPGAGGGGCR GVDRRHWVSE CKAKQSYVRA LTADAQGRVG WRWIRIDTAC VCTLLSRTGR A

Tag

None

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Purity

> 97 % by SDS-PAGE and HPLC analyses.

Biological Activity

The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures is less than 50 ng/mL, corresponding to a specific activity of > 2.0 × 104 IU/mg. Fully biologically active when compared to standard. 

Endotoxin

1.0 EU per 1μg of the protein by the LAL method.

Formulation

Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 5.5.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20. Further dilutions should be made in appropriate buffered solutions.

 

Shipping and Storage

The products are shipped with ice pack and can be stored at -20 for 1 year.

1 month, 2 to 8 °C under sterile conditions after reconstitution.
3 months, -20 °C under sterile conditions after reconstitution.

Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles.

 

Cautions  

  1. Avoid repeated freeze-thaw cycles.
  2. For your safety and health, please wear lab coats and disposable gloves for operation.
  3. For research use only.

 

HB240523